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Harvard Health Publishing, Harvard Medical School


Learn about treatment for Lyme disease, including possible side effects.

Lyme disease is a bacterial infection that is treated with antibiotics. Treatment typically lasts 10 days to a few weeks, depending on the stage and severity of the infection. 

Early Lyme disease is treated with a course of oral antibiotics. The antibiotics doxycycline, amoxicillin, and cefuroxime can all be used to treat Lyme disease. Doxycycline is also effective against some other tick-borne illnesses, including anaplasmosis, Borrelia miyamotoi disease, and Ehrlichiosis, though it is not effective against others like babesiosis (see Other Tick-Borne Diseases).